Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling

We reported that transgenic expression of the bone morphogenetic protein (BMP) signaling inhibitor noggin in the mouse stomach, leads to parietal-cell (PC) loss, expansion of transitional cells expressing markers of both mucus neck and zymogenic lineages, and to activation of proliferative mechanism...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Todisco, Andrea, Mao, Maria, Keeley, Theresa M, Ye, Wei, Samuelson, Linda C, Eaton, Kathryn A
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562585/
https://ncbi.nlm.nih.gov/pubmed/26290525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12501
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