Impaired osteogenesis in Menkes disease-derived induced pluripotent stem cells

INTRODUCTION: Bone abnormalities, one of the primary manifestations of Menkes disease (MD), include a weakened bone matrix and low mineral density. However, the molecular and cellular mechanisms underlying these bone defects are poorly understood. METHODS: We present in vitro modeling for impaired o...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Kim, Dongkyu, Choi, Jieun, Han, Kyu-Min, Lee, Beom Hee, Choi, Jin-Ho, Yoo, Han-Wook, Han, Yong-Mahn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562349/
https://ncbi.nlm.nih.gov/pubmed/26347346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0147-5
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