p53 Regulates FAK Expression in Human Tumor Cells

Attenuation of the p53 protein is one of the most common abnormalities in human tumors. Another important marker of tumorigenesis is focal adhesion kinase (FAK), a 125-kDa tyrosine kinase that is overexpressed at the mRNA and protein levels in a variety of human tumors. FAK is a critical regulator o...

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Udgivet i:Mol Carcinog
Main Authors: Golubovskaya, Vita M., Finch, Richard, Kweh, Frederick, Massoll, Nicole A., Campbell-Thompson, Martha, Wallace, Margaret R., Cance, William G.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562219/
https://ncbi.nlm.nih.gov/pubmed/17999388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20395
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