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Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer

Overexpression of the miR-17-92 cluster is a key oncogenic event in various cancer types. The oncogenic effect of the miR-17-92 cluster is enhanced by cooperation between its members in targeting tumor-suppressive proteins and pathways such as PTEN and TGFβ signaling. However, in the case of miR-19a...

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Pubblicato in:Front Med (Lausanne)
Autori principali: Fuziwara, Cesar Seigi, Kimura, Edna Teruko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561802/
https://ncbi.nlm.nih.gov/pubmed/26442266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2015.00064
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