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Antidepressant-like effects of guanfacine and sex-specific differences in c-fos immunoreactivity and paired-pulse ratio in male and female mice

RATIONALE: The α2a-noradrenergic agonist guanfacine decreases stress-induced smoking in female, but not male, human smokers. It is not known whether these effects are due to effects on mood regulation and/or result from nicotinic-cholinergic interactions. OBJECTIVES: To determine whether there are s...

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Bibliographische Detailangaben
Veröffentlicht in:Psychopharmacology (Berl)
Hauptverfasser: Mineur, Yann S., Bentham, Matthew P., Zhou, Wen-Liang, Plantenga, Margreet E., McKee, Sherry A., Picciotto, Marina R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561580/
https://ncbi.nlm.nih.gov/pubmed/26146014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-4001-3
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