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MF59- and Al(OH)(3)-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers
Staphylococcus aureus (S. aureus) is an important opportunistic pathogen that may cause invasive life-threatening infections, like sepsis and pneumonia. Due to the increasing antibiotic resistance, the development of an effective vaccine against S. aureus is needed. Although a correlate of protectio...
Enregistré dans:
Publié dans: | Front Immunol |
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Frontiers Media S.A.
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561515/ https://ncbi.nlm.nih.gov/pubmed/26441955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00439 |
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