MF59- and Al(OH)(3)-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers

Staphylococcus aureus (S. aureus) is an important opportunistic pathogen that may cause invasive life-threatening infections, like sepsis and pneumonia. Due to the increasing antibiotic resistance, the development of an effective vaccine against S. aureus is needed. Although a correlate of protectio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Monaci, Elisabetta, Mancini, Francesca, Lofano, Giuseppe, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Giraldi, Monica, Galletti, Bruno, Rossi Paccani, Silvia, Torre, Antonina, Fontana, Maria Rita, Grandi, Guido, de Gregorio, Ennio, Bensi, Giuliano, Chiarot, Emiliano, Nuti, Sandra, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561515/
https://ncbi.nlm.nih.gov/pubmed/26441955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00439
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