Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

Combining genotype data across cohorts increases power to estimate the heritability due to common single nucleotide polymorphisms (SNPs), based on analyzing a Genetic Relationship Matrix (GRM). However, the combination of SNP data across multiple cohorts may lead to stratification, when for example,...

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Detalhes bibliográficos
Publicado no:Behav Genet
Main Authors: Fedko, Iryna O., Hottenga, Jouke-Jan, Medina-Gomez, Carolina, Pappa, Irene, van Beijsterveldt, Catharina E. M., Ehli, Erik A., Davies, Gareth E., Rivadeneira, Fernando, Tiemeier, Henning, Swertz, Morris A., Middeldorp, Christel M., Bartels, Meike, Boomsma, Dorret I.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561077/
https://ncbi.nlm.nih.gov/pubmed/26036992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-015-9725-7
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