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Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer

INTRODUCTION: HOX genes play vital roles in growth and development, however, atypical redeployment of these genes is often associated with steroidal adaptability in endocrine cancers. We previously identified HOXC11 to be an indicator of poor response to hormonal therapy in breast cancer. In this st...

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Publicat a:Breast Cancer Res
Autors principals: Ali, Azlena, Creevey, Laura, Hao, Yuan, McCartan, Damian, O’Gaora, Peadar, Hill, Arnold, Young, Leonie, McIlroy, Marie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560928/
https://ncbi.nlm.nih.gov/pubmed/26341737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0636-6
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