The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc

INTRODUCTION: In the present study, we sought to quantify and contrast the secretome and biomechanical properties of the non-chondrodystrophic (NCD) and chondrodystrophic (CD) canine intervertebral disc (IVD) nucleus pulposus (NP). METHODS: We used iTRAQ proteomic methods to quantify the secretome o...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Erwin, William Mark, DeSouza, Leroi, Funabashi, Martha, Kawchuk, Greg, Karim, Muhammad Zia, Kim, Sarah, Mӓdler, Stefanie, Matta, Ajay, Wang, Xiaomei, Mehrkens, K. Arne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560915/
https://ncbi.nlm.nih.gov/pubmed/26341258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0733-z
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