Polymorphisms on PAI-1 and ACE genes in association with fibrinolytic bleeding after on-pump cardiac surgery

BACKGROUND: Carriers of plasminogen activator inhibitor -1 (PAI-1) -675 genotype 5G/5G may be associated with lower preoperative PAI-1 plasma levels and higher blood loss after heart surgery using cardiopulmonary bypass (CPB). We speculate if polymorphisms of PAI-1 -844 A/G and angiotensin convertin...

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Bibliographic Details
Published in:BMC Anesthesiol
Main Authors: Ozolina, Agnese, Strike, Eva, Nikitina-Zake, Liene, Jaunalksne, Inta, Krumina, Angelika, Lacis, Romans, Bjertnaes, Lars J., Vanags, Indulis
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560913/
https://ncbi.nlm.nih.gov/pubmed/26340801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-015-0101-1
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