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Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria
Current methods for producing immunoglobulin G (IgG) antibodies in engineered cells often require refolding steps or secretion across one or more biological membranes. Here, we describe a robust expression platform for biosynthesis of full-length IgG antibodies in the Escherichia coli cytoplasm. Syn...
में बचाया:
| में प्रकाशित: | Nat Commun |
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| मुख्य लेखकों: | , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Pub. Group
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560801/ https://ncbi.nlm.nih.gov/pubmed/26311203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9072 |
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