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Real-time imaging reveals local, transient vascular permeability and tumor cell intravasation stimulated by Tie2(Hi) macrophage-derived VEGFA

Dissemination of tumor cells is an essential step in metastasis. Direct contact between a macrophage, Mena over-expressing tumor cell and endothelial cell [Tumor MicroEnvironment of Metastasis (TMEM)], correlates with metastasis in breast cancer patients. Here we show, using intravital high-resoluti...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Principais autores: Harney, Allison S., Arwert, Esther N., Entenberg, David, Wang, Yarong, Guo, Peng, Qian, Bin-Zhi, Oktay, Maja H., Pollard, Jeffrey W., Jones, Joan G., Condeelis, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560669/
https://ncbi.nlm.nih.gov/pubmed/26269515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0012
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