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Ultrasound-assisted non-viral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion

RATIONALE: Xerostomia is a common side effect of ionizing radiation used to treat head and neck cancer. A groundbreaking Phase I human clinical trial utilizing Adenoviral gene transfer of Aquaporin-1 (AQP1) to a single salivary gland of individuals suffering from radiation-induced xerostomia has rec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Gene Ther
Prif Awduron: Wang, Z, Zourelias, L, Wu, C, Edwards, PC, Trombetta, M, Passineau, MJ
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560616/
https://ncbi.nlm.nih.gov/pubmed/25871828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.36
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