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Insight into the mechanism of polyphenols on the activity of HMGR by molecular docking

Statins are hypolipidemic drugs that are effective in the treatment of hypercholesterolemia by attenuating cholesterol synthesis in the liver via competitive inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Recently, dietary changes associated with drug therapy have garnered...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Islam, Barira, Sharma, Charu, Adem, Abdu, Aburawi, Elhadi, Ojha, Shreesh
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560516/
https://ncbi.nlm.nih.gov/pubmed/26357462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86705
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