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Protein Post-Translational Modifications and Misfolding: New Concepts in Heart Failure

A new concept in the field of heart failure research points to a role of misfolded proteins, forming pre-amyloid oligomers (PAOs), in cardiac toxicity. This is largely based on few studies reporting the presence of PAOs, similar to those observed in neurodegenerative disease, in experimental models...

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Bibliographic Details
Published in:Proteomics Clin Appl
Main Authors: del Monte, Federica, Agnetti, Giulio
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560347/
https://ncbi.nlm.nih.gov/pubmed/24946239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201400037
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