Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts

Exosomes derived from solid tumor cells are involved in immune suppression, angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been less investigated. The pathogenesis of chronic lymphocytic leukemia (CLL) is stringently associated with a tumor-supportive microenvironment an...

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Detalles Bibliográficos
Publicado en:Blood
Autores principales: Paggetti, Jerome, Haderk, Franziska, Seiffert, Martina, Janji, Bassam, Distler, Ute, Ammerlaan, Wim, Kim, Yeoun Jin, Adam, Julien, Lichter, Peter, Solary, Eric, Berchem, Guy, Moussay, Etienne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2015
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560344/
https://ncbi.nlm.nih.gov/pubmed/26100252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-618025
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