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Disulfide Cross-linked Micelles for the Targeted Delivery of Vincristine to B-cell Lymphoma

Vincristine (VCR) is a potent anti-cancer drug but its clinical efficacy is dose-limited by severe neurotoxicity. Prophylactic and palliative treatment of VCR-induced toxicity have been explored without significant findings. The field of drug delivery may provide an opportunity to increase the thera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Kato, Jason, Li, Yuanpei, Xiao, Kai, Lee, Joyce, Luo, Juntao, Tuscano, Joseph M., O’Donnell, Robert T., Lam, Kit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560237/
https://ncbi.nlm.nih.gov/pubmed/22530955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300128b
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