P2X7 receptor-mediated PARP1 activity regulates astroglial death in the rat hippocampus following status epilepticus

Poly(ADP-ribose) polymerase-1 (PARP1) plays a regulatory role in apoptosis, necrosis, and other cellular processes after injury. Recently, we revealed that PARP1 regulates the differential neuronal/astroglial responses to pilocarpine-induced status epilepticus (SE) in the distinct brain regions. In...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Kim, Ji Yang, Ko, Ah-Reum, Kim, Ji-Eun
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560025/
https://ncbi.nlm.nih.gov/pubmed/26388738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00352
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