Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants

Sickle cell disease (SCD) and thalassemias (Thal) are common congenital disorders, which can be diagnosed early in gestation and result in significant morbidity and mortality. Hematopoietic stem cell transplantation, the only curative therapy for SCD and Thal, is limited by the absence of matched do...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Peranteau, William H., Hayashi, Satoshi, Abdulmalik, Osheiza, Chen, Qiukan, Merchant, Aziz, Asakura, Toshio, Flake, Alan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559936/
https://ncbi.nlm.nih.gov/pubmed/26124498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-636803
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