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Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide

[Image: see text] Polyethylene glycol-functionalized nanographene oxide (PEGylated n-GO) was synthesized from alkyne-modified n-GO, using solvent-free click-mechanochemistry, i.e., copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC). The modified n-GO was subsequently conjugated to a mucin 1 rece...

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Veröffentlicht in:ACS Appl Mater Interfaces
Hauptverfasser: Rubio, Noelia, Mei, Kuo-Ching, Klippstein, Rebecca, Costa, Pedro M., Hodgins, Naomi, Wang, Julie Tzu-Wen, Festy, Frederic, Abbate, Vincenzo, Hider, Robert C., Chan, Ka Lung Andrew, Al-Jamal, Khuloud T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2015
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559840/
https://ncbi.nlm.nih.gov/pubmed/26278410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.5b06250
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