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MicroRNA-34a inhibits human trophoblast cell invasion by targeting MYC

BACKGROUND: Preeclampsia, one of the major disorders of pregnancy, is characterized by inadequate trophoblast invasion and defective trophoblast-mediated remodeling of placental vasculature. MicroRNA-34a (miR-34a) has been found to be aberrantly expressed in the placentas of preeclamptic patients, y...

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Publié dans:BMC Cell Biol
Auteurs principaux: Sun, Manni, Chen, Haiying, Liu, Jing, Tong, Chunxiao, Meng, Tao
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559296/
https://ncbi.nlm.nih.gov/pubmed/26335888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0068-2
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