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Mutation status concordance between primary lesions and metastatic sites of advanced non-small-cell lung cancer and the impact of mutation testing methodologies: a literature review

Increased understanding of the genetic aetiology of advanced non-small-cell lung cancer (aNSCLC) has facilitated personalised therapies that target specific molecular aberrations associated with the disease. Biopsy samples for mutation testing may be taken from primary or metastatic sites, depending...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Sherwood, James, Dearden, Simon, Ratcliffe, Marianne, Walker, Jill
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559261/
https://ncbi.nlm.nih.gov/pubmed/26338018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0207-9
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