Zoster Vaccination Increases the Breadth of CD4(+) T Cells Responsive to Varicella Zoster Virus

Background. The live, attenuated varicella vaccine strain (vOka) is the only licensed therapeutic vaccine. Boost of varicella zoster virus (VZV)–specific cellular immunity is a likely mechanism of action. We examined memory CD4(+) T-cell responses to each VZV protein at baseline and after zoster vac...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Laing, Kerry J., Russell, Ronnie M., Dong, Lichun, Schmid, D. Scott, Stern, Michael, Magaret, Amalia, Haas, Jürgen G., Johnston, Christine, Wald, Anna, Koelle, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559191/
https://ncbi.nlm.nih.gov/pubmed/25784732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv164
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