Comparison of stranded and non-stranded RNA-seq transcriptome profiling and investigation of gene overlap

BACKGROUND: While RNA-sequencing (RNA-seq) is becoming a powerful technology in transcriptome profiling, one significant shortcoming of the first-generation RNA-seq protocol is that it does not retain the strand specificity of origin for each transcript. Without strand information it is difficult an...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Zhao, Shanrong, Zhang, Ying, Gordon, William, Quan, Jie, Xi, Hualin, Du, Sarah, von Schack, David, Zhang, Baohong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559181/
https://ncbi.nlm.nih.gov/pubmed/26334759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1876-7
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