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Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription

BACKGROUND: In the Metazoan nucleus, core histones assemble the genomic DNA to form nucleosome arrays, which are further compacted into dense chromatin structures by the linker histone H1. The extraordinary density of chromatin creates an obstacle for accessing the genetic information. Regulation of...

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Pubblicato in:Epigenetics Chromatin
Autori principali: Zhang, Qian, Giebler, Holli A., Isaacson, Marisa K., Nyborg, Jennifer K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558729/
https://ncbi.nlm.nih.gov/pubmed/26339295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0022-8
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