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CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X
Current antiviral therapies cannot cure hepatitis B virus (HBV) infection; successful HBV eradication would require inactivation of the viral genome, which primarily persists in host cells as episomal covalently closed circular DNA (cccDNA) and, to a lesser extent, as chromosomally integrated sequen...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558539/ https://ncbi.nlm.nih.gov/pubmed/26334116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13734 |
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