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Uncovering major genomic features of essential genes in Bacteria and a methanogenic Archaea

Identification of essential genes is critical to understand the physiology of a species, propose novel drug targets and uncover minimal gene sets required for life. Although essential gene sets of several organisms have been determined using large-scale mutagenesis techniques, systematic studies add...

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Udgivet i:FEBS J
Main Authors: Grazziotin, Ana Laura, Vidal, Newton Medeiros, Venancio, Thiago Motta
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558319/
https://ncbi.nlm.nih.gov/pubmed/26084810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13350
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