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Doxorubicin and Cyclophosphamide Induce Cognitive Dysfunction and Activate the ERK and AKT Signaling Pathways

Chemotherapy is associated with long-term cognitive deficits in breast cancer survivors. Studies suggest that these impairments result in the loss of cognitive reserve and/or induce a premature aging of the brain. This study has been aimed to determine the potential underlying mechanisms that induce...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Salas-Ramirez, Kaliris Y, Bagnall, Ciara, Frias, Leslie, Abdali, Syed A, Ahles, Tim A., Hubbard, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558256/
https://ncbi.nlm.nih.gov/pubmed/26099816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.06.028
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