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Meniscus is more susceptible than cartilage to catabolic and anti-anabolic effects of adipokines

OBJECTIVE: This study compared the effects on cartilage and meniscus matrix catabolism and biosynthesis of several adipokines implicated in osteoarthritis. DESIGN: Cartilage and meniscus explants were cultured for 1 or 9 days in serum-free medium alone or with 0.02, 0.2, or 2μg/ml of leptin, visfati...

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Détails bibliographiques
Publié dans:Osteoarthritis Cartilage
Auteurs principaux: Nishimuta, James F., Levenston, Marc E.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558246/
https://ncbi.nlm.nih.gov/pubmed/25917638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.04.014
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