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AIP1 expression in tumor niche suppresses tumor progression and metastasis

Studies from tumor cells suggest that tumor suppressor AIP1 inhibits epithelial-mesenchymal transition (EMT). However, the role of AIP1 in the tumor microenvironment has not been examined. We show that a global or vascular endothelial cell (EC)-specific deletion of the AIP1 gene in mice augments tum...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ji, Weidong, Li, Yonghao, He, Yun, Yin, Mingzhu, Zhou, Huanjiao Jenny, Boggon, Titus J., Zhang, Haifeng, Min, Wang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558200/
https://ncbi.nlm.nih.gov/pubmed/26139244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0088
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