Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis

The most abundant populations of non-neoplastic cells in the glioblastoma (GBM) microenvironment are resident microglia, macrophages and infiltrating monocytes from the blood circulation. The mechanisms by which monocytes infiltrate into GBM, their fate following infiltration, and their role in GBM...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Feng, Xi, Szulzewsky, Frank, Yerevanian, Alexan, Chen, Zhihong, Heinzmann, David, Rasmussen, Rikke Darling, Alvarez-Garcia, Virginia, Kim, Yeonghwan, Wang, Bingcheng, Tamagno, Ilaria, Zhou, Hao, Li, Xiaoxia, Kettenmann, Helmut, Ransohoff, Richard M., Hambardzumyan, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558137/
https://ncbi.nlm.nih.gov/pubmed/25987130
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