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Thyroid hormone and anti-apoptosis in tumor cells

The principal secretory product of the thyroid gland, L-thyroxine (T(4)), is anti-apoptotic at physiological concentrations in a number of cancer cell lines. Among the mechanisms of anti-apoptosis activated by the hormone are interference with the Ser-15 phosphorylation (activation) of p53 and with...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Hung-Yun, Glinsky, Gennadi V., Mousa, Shaker A., Davis, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558111/
https://ncbi.nlm.nih.gov/pubmed/26041883
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