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Functions of Peptidoglycan Recognition Proteins (Pglyrps) at the Ocular Surface: Bacterial Keratitis in Gene-Targeted Mice Deficient in Pglyrp-2, -3 and -4

PURPOSE: Functions of antimicrobial peptidoglycan recognition proteins (Pglyrp1-4) at the ocular surface are poorly understood. Earlier, we reported an antibacterial role for Pglyrp-1 in Pseudomonas aeruginosa keratitis. Here we investigated functions of three other related genes Pglyrp-2, -3 and -4...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gowda, Ranjita N., Redfern, Rachel, Frikeche, Jihane, Pinglay, Sudarshan, Foster, James William, Lema, Carolina, Cope, Leslie, Chakravarti, Shukti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558058/
https://ncbi.nlm.nih.gov/pubmed/26332373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137129
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