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An efficient method for the preparation of peracetylated Neu5Ac2en by flash vacuum pyrolysis
[Image: see text] Peracetylated Neu5Ac2en methyl ester, an intermediate in the synthesis of the influenza neuraminidase inhibitor Relenza, has been synthesized in high yields from peracetylated Neu5Ac methyl ester by flash vacuum pyrolysis. Mechanistic evidence including deuterium labeled studies an...
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| Publicado no: | J Org Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557971/ https://ncbi.nlm.nih.gov/pubmed/19413276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo900224t |
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