Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study

BACKGROUND: Telomerase reverse transcriptase (TERT) maintains telomere ends during DNA replication by catalyzing the addition of short telomere repeats. The expression of telomerase is normally repressed in somatic cells leading to a gradual shortening of telomeres and cellular senescence with aging...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Bressler, Jan, Franceschini, Nora, Demerath, Ellen W., Mosley, Thomas H., Folsom, Aaron R., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557920/
https://ncbi.nlm.nih.gov/pubmed/26201603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0194-x
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