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Targeting the B Cell Receptor Pathway in Chronic Lymphocytic Leukemia

The B cell receptor (BCR) pathway plays a crucial role in the survival, proliferation, and trafficking of chronic lymphocytic leukemia (CLL) cells. Inhibitors of the key kinases in this pathway, including spleen tyrosine kinase (SYK), mammalian target of rapamycin (mTOR), phosphoinositide 3’-kinase...

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Publicado en:Leuk Lymphoma
Main Authors: Davids, Matthew S., Brown, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557770/
https://ncbi.nlm.nih.gov/pubmed/22616724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.695781
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