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Label-free Detection of Missense Mutations and Methylation Differences in the p53 Gene Using Optically Diffracting Hydrogels

We have developed a novel approach for DNA detection as well as genetic screening of mutations by uniquely combining DNA-responsive and optically diffracting materials. This approach entails the polymerization of a photonic crystal within a hydrogel network that alters the diffraction of light in re...

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Detalhes bibliográficos
Publicado no:Analyst
Main Authors: MacConaghy, Kelsey I., Chadly, Duncan M., Stoykovich, Mark P., Kaar, Joel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557741/
https://ncbi.nlm.nih.gov/pubmed/26270146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an01191d
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