Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis

CD4 T-cell help is not a universal requirement for effective primary CD8 T cells but is essential to generate memory CD8 T cells capable of recall responses. This study examined how CD4 T cells affect primary and secondary anti-viral CD8 T-cell responses within the central nervous system (CNS) durin...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Hwang, Mihyun, Phares, Timothy W, Hinton, David R, Stohlman, Stephen A, Bergmann, Cornelia C, Min, Booki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557674/
https://ncbi.nlm.nih.gov/pubmed/25187405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12378
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