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Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease

Animals that accurately model human disease are invaluable in medical research, allowing a critical understanding of disease mechanisms, and the opportunity to evaluate the effect of therapeutic compounds in pre-clinical studies. Many types of animal models are used world-wide, with the most common...

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Podrobná bibliografie
Vydáno v:Orphanet J Rare Dis
Hlavní autoři: Pinnapureddy, Ashish R., Stayner, Cherie, McEwan, John, Baddeley, Olivia, Forman, John, Eccles, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557632/
https://ncbi.nlm.nih.gov/pubmed/26329332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-015-0327-5
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