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Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1

BACKGROUND: Blood platelet numbers are correlated with growth and aggressiveness of several tumor types, including hepatocellular carcinoma (HCC). We previously found that platelet lysates (hPLs) both stimulated HCC cell growth and migration, and antagonized the growth-inhibitory and apoptotic effec...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Lippolis, Catia, Refolo, Maria Grazia, D’Alessandro, Rosalba, Carella, Nicola, Messa, Caterina, Cavallini, Aldo, Carr, Brian Irving
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557596/
https://ncbi.nlm.nih.gov/pubmed/26329608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0210-1
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