Defective trained immunity in patients with STAT-1-dependent chronic mucocutaneaous candidiasis

Patients with signal transducer and activator of transcription-1 (STAT1)-dependent chronic mucocutaneous candidiasis (CMC) and patients with STAT3-dependent hyper-immunoglobulin (Ig)E syndrome (HIES) display defects in T helper type 17 (Th17) cytokine production capacity. Despite this similar immune...

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Bibliographic Details
Published in:Clin Exp Immunol
Main Authors: Ifrim, D C, Quintin, J, Meerstein-Kessel, L, Plantinga, T S, Joosten, L A B, van der Meer, J W M, van de Veerdonk, F L, Netea, M G
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Translational
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557379/
https://ncbi.nlm.nih.gov/pubmed/25880788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12642
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