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Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS
Ca(2+) signals are highly regulated in a spatiotemporal manner in numerous cellular physiological events. Here we report a genetically engineered blue light-activated Ca(2+) channel switch (BACCS), as an optogenetic tool for generating Ca(2+) signals. BACCS opens Ca(2+)-selective ORAI ion channels i...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557345/ https://ncbi.nlm.nih.gov/pubmed/26282514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9021 |
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