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Formation of helical membrane tubes around microtubules by single-headed kinesin KIF1A

The kinesin-3 motor KIF1A is in charge of vesicular transport in neuronal axons. Its single-headed form is known to be very inefficient due to the presence of a diffusive state in the mechanochemical cycle. However, recent theoretical studies have suggested that these motors could largely enhance fo...

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Pubblicato in:Nat Commun
Autori principali: Oriola, David, Roth, Sophie, Dogterom, Marileen, Casademunt, Jaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557341/
https://ncbi.nlm.nih.gov/pubmed/26268542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9025
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