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Endothelial cell tumor growth is Ape/ref-1 dependent

Tumor-forming endothelial cells have highly elevated levels of Nox-4 that release H(2)O(2) into the nucleus, which is generally not compatible with cell survival. We sought to identify compensatory mechanisms that enable tumor-forming endothelial cells to survive and proliferate under these conditio...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Biswas, Ayan, Khanna, Savita, Roy, Sashwati, Pan, Xueliang, Sen, Chandan K., Gordillo, Gayle M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556895/
https://ncbi.nlm.nih.gov/pubmed/26108661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00022.2015
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