Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung

Pulmonary infections caused by Pseudomonas aeruginosa are a recalcitrant problem in cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary patterns of these infections are well studied, we know little about the short-term population dynamics that enable this pathog...

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Veröffentlicht in:mBio
Hauptverfasser: Diaz Caballero, Julio, Clark, Shawn T., Coburn, Bryan, Zhang, Yu, Wang, Pauline W., Donaldson, Sylva L., Tullis, D. Elizabeth, Yau, Yvonne C. W., Waters, Valerie J., Hwang, David M., Guttman, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556809/
https://ncbi.nlm.nih.gov/pubmed/26330513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00981-15
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