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Effects of silymarin on neuropathic pain and formalin-induced nociception in mice

OBJECTIVE(S): Based on the previous reports, silymarin can suppress nitric oxide, prostaglandin E2 (PGE2), leukotrienes, cytokines production, and neutrophils infiltration. Regarding the fact that inflammation plays an important role in neuropathic and formalin-induced pain, it was assumed that sily...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Hassani, Faezeh Vahdati, Rezaee, Ramin, Sazegara, Hasan, Hashemzaei, Mahmoud, Shirani, Kobra, Karimi, Gholamreza
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556767/
https://ncbi.nlm.nih.gov/pubmed/26351564
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