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Role of Ryanodine and NMDA Receptors in Tetrabromobisphenol A-Induced Calcium Imbalance and Cytotoxicity in Primary Cultures of Rat Cerebellar Granule Cells

The study assessed the role of ryanodine receptors (RyRs) and NMDA receptors (NMDARs) in the Ca(2+) transients and cytotoxicity induced in neurons by the brominated flame retardant tetrabromobisphenol A (TBBPA). Primary cultures of rat cerebellar granule cells (CGC) were exposed to 7.5, 10, or 25 µM...

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Detalhes bibliográficos
Publicado no:Neurotox Res
Main Authors: Zieminska, Elzbieta, Stafiej, Aleksandra, Toczylowska, Beata, Albrecht, Jan, Lazarewicz, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556744/
https://ncbi.nlm.nih.gov/pubmed/26215658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-015-9546-8
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