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A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE

Angiotensin converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase with an essential role in blood pressure homeostasis in mammals. ACE has long been targeted in the treatment of hypertension through ACE inhibitors, however current inhibitors are known to cause severe side effects....

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Harrison, Charlotte, Acharya, K. Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556727/
https://ncbi.nlm.nih.gov/pubmed/26380810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.004
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