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The RNA Binding Protein Igf2bp1 Is Required for Zebrafish RGC Axon Outgrowth In Vivo

Attractive growth cone turning requires Igf2bp1-dependent local translation of β-actin mRNA in response to external cues in vitro. While in vivo studies have shown that Igf2bp1 is required for cell migration and axon terminal branching, a requirement for Igf2bp1 function during axon outgrowth has no...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gaynes, John A., Otsuna, Hideo, Campbell, Douglas S., Manfredi, John P., Levine, Edward M., Chien, Chi-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556669/
https://ncbi.nlm.nih.gov/pubmed/26325373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134751
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